Article
Molecular analysis of the pathogenesis of autoimmune insulitis in NOD mice.
The Tohoku journal of experimental medicine - 1 May 1994
Koide Y, Kaidoh T, Nakamura M, Yoshida T O
Abstract excerpt
Among diabetes-susceptibility genes in NOD mice, only Idd-1 has been clearly assigned: Idd-1 could be a gene complex composed of class II major histocompatibility complex (MHC) genes, I-A beta and I-E. Employing restriction fragment length polymorphism (RFLP) analysis and nucleotide sequencing, w...
Topics
- Amino Acid Sequence
- Animals
- Autoimmune Diseases
- Base Sequence
- Cell Movement
- Diabetes Mellitus
- Gene Expression
- Genes
- Genes, MHC Class II
- Genetic Predisposition to Disease
- Inflammation
- Islets of Langerhans
- Lymphocytes
- Mice
- Mice, Inbred NOD
- Mice, Inbred Strains
- Molecular Probes
- Molecular Sequence Data
