Article
In vivo regulation of the mouse beta myosin heavy chain gene.
The Journal of biological chemistry - 9 Dec 1994
Knotts S, Rindt H, Neumann J, Robbins J
Abstract excerpt
The interactions of trans-acting factors with their respective cis-acting elements in the 5' upstream region of the beta myosin heavy chain gene (MyHC) regulate its tissue- and developmental stage-specific expression. The role of three conserved elements, an MCAT or TEF-1 binding site, a C-rich region, and a beta e3 region, in muscle-specific gene expression was analyzed in vivo. Each cis-acting site was ablated...
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