Article
In vivo regulation of the mouse beta myosin heavy chain gene.
The Journal of biological chemistry - 9 Dec 1994
Knotts S, Rindt H, Neumann J, Robbins J
Abstract excerpt
The interactions of trans-acting factors with their respective cis-acting elements in the 5' upstream region of the beta myosin heavy chain gene (MyHC) regulate its tissue- and developmental stage-specific expression. The role of three conserved elements, an MCAT or TEF-1 binding site, a C-rich r...
Topics
- Animals
- Base Sequence
- DNA Primers
- Mice
- Mice, Transgenic
- Molecular Sequence Data
- Muscle, Skeletal
- Mutation
- Myocardium
- Myosins
- Promoter Regions, Genetic
