Transgenic analysis of the thyroid-responsive elements in the alpha-cardiac myosin heavy chain gene promoter.

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Article

Transgenic analysis of the thyroid-responsive elements in the alpha-cardiac myosin heavy chain gene promoter.

The Journal of biological chemistry - 25 Feb 1993

Subramaniam A, Gulick J, Neumann J, Knotts S, Robbins J

Abstract excerpt

The role of two putative, cis-acting thyroid hormone-responsive elements, TRE1 and TRE2, located at -129 to -149 and -102 to -120, respectively, on the murine alpha-myosin heavy chain (MHC) gene, has been investigated in transgenic mice. These motifs are present in a 4.5-kilobase fragment lying u...

Topics

Animals
Base Sequence
Chloramphenicol O-Acetyltransferase
DNA
Gene Expression Regulation
Mice
Mice, Transgenic
Molecular Sequence Data
Mutation
Myocardium
Myosins
Promoter Regions, Genetic
Thyroid Hormones

Source

Open in PubMed

Identifiers

PMID: 8440718

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8440718-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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