Myocyte enhancer factor-2 and serum response factor binding elements regulate fast Myosin heavy chain transcription in vivo.

Abstract excerpt

Adult fast muscle fibers express distinct myosin heavy chains (MyHC) in differing proportions, but the mechanisms underlying their differential expression remain undefined. We used a variety of in vitro and in vivo approaches to explore the contribution of transcriptional regulation to adult fast MyHC expression. Here we show that 800-1000 bp of a sequence upstream of the three mouse adult fast MyHC genes (Ia,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Luciferases
• Share to MEF2 Transcription Factors