An in vivo analysis of transcriptional elements in the mouse alpha-myosin heavy chain gene promoter.

doi:10.1007/BF01973758

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

An in vivo analysis of transcriptional elements in the mouse alpha-myosin heavy chain gene promoter.

Transgenic research - 1 Nov 1995

Rindt H, Subramaniam A, Robbins J

Abstract excerpt

During development in the murine ventricle, there is a switch in myosin heavy chain gene (MyHC) transcription. The beta-MyHC is expressed in the ventricles during foetal development, but is shut down at or around birth, at which time alpha-MyHC transcription is activated. This antithetical switch is thought to be mediated by circulating levels of thyroid hormone (TH) and both low and high affinity thyroid...

Topics

Animals
Atrial Function
Base Sequence
Chloramphenicol O-Acetyltransferase
Gene Expression Regulation, Developmental
Hyperthyroidism
Mice
Mice, Transgenic
Molecular Sequence Data
Mutation
Myosin Heavy Chains

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Promoter Regions, Genetic

Recombinant Fusion Proteins

Thyroid Gland

Thyroxine

Transcription, Genetic

Transgenes

Ventricular Function

Source

Open in PubMed

Identifiers

PMID: 7581520
DOI: 10.1007/BF01973758

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7581520-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An in vivo analysis of transcriptional elements in the mouse alpha-myosin heavy chain gene promoter.PMID 7581520Read ↗

Transgenic analysis of the thyroid-responsive elements in the alpha-cardiac myosin heavy chain gene promoter.Semantic proximity Read ↗

Control of cardiac myosin heavy chain gene expressionSemantic proximity Read ↗

In vivo regulation of the mouse beta myosin heavy chain gene.Semantic proximity Read ↗

CRE and TRE sequences of the rat tyrosine hydroxylase promoter are required for TH basal expression in adult mice but not in the embryo.Semantic proximity Read ↗

Reengineering Inducible Cardiac-Specific Transgenesis With an Attenuated Myosin Heavy Chain PromoterSemantic proximity Read ↗

Cardiac transgenesis with the tetracycline transactivator changes myocardial function and gene expression.Semantic proximity Read ↗

Transcription factor RTEF-1 mediates alpha1-adrenergic reactivation of the fetal gene program in cardiac myocytes.Semantic proximity Read ↗

Transcriptional Targeting Approaches in Cardiac Gene Transfer Using AAV VectorsSemantic proximity Read ↗

Rescue of high expression beta-tropomyosin transgenic mice by 5-propyl-2-thiouracil. Regulating the alpha-myosin heavy chain promoter.Semantic proximity Read ↗

Basal and alpha1-adrenergic-induced activity of minimal rat betaMHC promoters in cardiac myocytes requires multiple TEF-1 but not NFAT binding sites.Semantic proximity Read ↗

In vivo regulation of the chicken cardiac troponin T gene promoter in zebrafish embryos.Semantic proximity Read ↗

The Thyrotropin-Releasing Hormone Gene Is Regulated by Thyroid Hormone at the Level of Transcription in VivoSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.