Article
An in vivo analysis of transcriptional elements in the mouse alpha-myosin heavy chain gene promoter.
Transgenic research - 1 Nov 1995
Rindt H, Subramaniam A, Robbins J
Abstract excerpt
During development in the murine ventricle, there is a switch in myosin heavy chain gene (MyHC) transcription. The beta-MyHC is expressed in the ventricles during foetal development, but is shut down at or around birth, at which time alpha-MyHC transcription is activated. This antithetical switch is thought to be mediated by circulating levels of thyroid hormone (TH) and both low and high affinity thyroid...
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