Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

M-CAT binding factor, a novel trans-acting factor governing muscle-specific transcription.

Molecular and cellular biology - 1 Aug 1990

Mar J H, Ordahl C P

Abstract excerpt

The cardiac troponin T (cTNT) promoter contains a highly muscle specific distal promoter element capable of conferring muscle-specific transcription from a heterologous TATA box-transcription initiation site. Three sequence motifs within this distal promoter element are conserved in the promoter and regulatory regions of many sarcomeric protein genes. Mutational analysis demonstrated that homologies to two of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Cells, Cultured
Share to DNA-Binding Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Probes

Share to Molecular Sequence Data

Share to Mutation

Share to Oligonucleotide Probes

Share to Promoter Regions, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 2370866
DOI: 10.1128/mcb.10.8.4271-4283.1990
PMCID: PMC360969

Genes

CAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

M-CAT binding factor, a novel trans-acting factor governing muscle-specific transcription.PMID 2370866Read ↗

MCAT Elements and the TEF-1 Family of Transcription Factors in Muscle Development and DiseaseSemantic proximity Read ↗

Muscle-enriched TEF-1 isoforms bind M-CAT elements from muscle-specific promoters and differentially activate transcription.Semantic proximity Read ↗

Identification of cis elements in the cardiac troponin T gene conferring specific expression in cardiac muscle of transgenic mice.Semantic proximity Read ↗

In vivo regulation of the chicken cardiac troponin T gene promoter in zebrafish embryos.Semantic proximity Read ↗

GATA elements control repression of cardiac troponin I promoter activity in skeletal muscle cells.Semantic proximity Read ↗

Transcription Enhancer Factor 1 Binds Multiple Muscle MEF2 and A/T-Rich Elements during Fast-to-Slow Skeletal Muscle Fiber Type TransitionsSemantic proximity Read ↗

Mef2c is an essential regulatory element required for unique expression of the cardiac-specific CARK gene.Semantic proximity Read ↗

Synergistic interactions between heterologous upstream activation elements and specific TATA sequences in a muscle-specific promoter.Semantic proximity Read ↗

Divergence in species and regulatory role of beta -myosin heavy chain proximal promoter muscle-CAT elements.Semantic proximity Read ↗

M-CAT element mediates mechanical stretch-activated transcription of B-type natriuretic peptide via ERK activation.Semantic proximity Read ↗

Transcription factor RTEF-1 mediates alpha1-adrenergic reactivation of the fetal gene program in cardiac myocytes.Semantic proximity Read ↗

Combinatorial cis-Acting Elements Control Tissue-specific Activation of the Cardiac Troponin I Gene in Vitro and in VivoSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.