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Article

Divergence in species and regulatory role of beta -myosin heavy chain proximal promoter muscle-CAT elements.

American journal of physiology. Cell physiology - 1 Dec 2002

Tsika Richard W, McCarthy John, Karasseva Natalia, Ou Yangsi, Tsika Gretchen L

Abstract excerpt

We examined the functional role of distinct muscle-CAT (MCAT) elements during non-weight-bearing (NWB) regulation of a wild-type 293-base pair beta-myosin heavy chain (beta MyHC) transgene. Electrophoretic mobility shift assays (EMSA) revealed decreased NTEF-1, poly(ADP-ribose) polymerase, and Max binding at the human distal MCAT element when using NWB soleus vs. control soleus nuclear extract. Compared with the...

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Identifiers

PMID: 12388056
DOI: 10.1152/ajpcell.00278.2002

Genes

MCAT
CAT
TEF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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