Article
Identification of cis elements in the cardiac troponin T gene conferring specific expression in cardiac muscle of transgenic mice.
Circulation research - 3 Mar 2000
Wang Q, Sigmund C D, Lin J J
Abstract excerpt
To investigate the underlying mechanism regulating cardiac gene expression, transgenic mice carrying the rat cardiac troponin T proximal promoter (-497 bp from the transcriptional start site) fused to a LacZ or chloramphenicol acetyltransferase (CAT) reporter gene were analyzed. The LacZ expression pattern throughout development was very similar to that of the endogenous cardiac troponin T gene. Within this...
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