Isolation and characterization of the mouse cardiac myosin heavy chain genes

doi:10.1016/s0021-9258(18)31568-0

Article

Isolation and characterization of the mouse cardiac myosin heavy chain genes

1 May 1991

Abstract excerpt

Two mouse genomic libraries were probed in order to isolate the murine cardiac myosin heavy chain (MHC) genes. Two overlapping cosmid clones that encode the cardiac genes were isolated. One of them encompasses the entire alpha-cardiac MHC gene, its 5'-flanking region and approximately 10 kilobase pairs (kb) of the 3'-end of the beta-cardiac MHC gene which we determined is located approximately 4 kb upstream of...

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