Article
Multiple functions of raf proto-oncogene during development from analysis of a temperature-sensitive mutation of Drosophila.
The International journal of developmental biology - 1 Jun 1994
Hata M, Inoue Y H, Yoo M A, Nishida Y
Abstract excerpt
A temperature-sensitive (ts) mutation of Drosophila melanogaster for D-raf, encoding a serine/threonine protein kinase, was newly induced by EMS-treatment. Temperature-shift experiments on the ts mutant revealed that D-raf is required during most of the developmental stages, and confirmed the previously reported roles of D-raf in the regulation of cell proliferation and in the determination of cell fates at...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.