Multiple functions of raf proto-oncogene during development from analysis of a temperature-sensitive mutation of Drosophila.

Article

Multiple functions of raf proto-oncogene during development from analysis of a temperature-sensitive mutation of Drosophila.

The International journal of developmental biology - 1 Jun 1994

Hata M, Inoue Y H, Yoo M A, Nishida Y

Abstract excerpt

A temperature-sensitive (ts) mutation of Drosophila melanogaster for D-raf, encoding a serine/threonine protein kinase, was newly induced by EMS-treatment. Temperature-shift experiments on the ts mutant revealed that D-raf is required during most of the developmental stages, and confirmed the pre...

Topics

Animals
Cell Cycle
Cell Division
Drosophila melanogaster
Embryonic and Fetal Development
Female
Genes, Insect
Male
Mutation
Proto-Oncogenes
Signal Transduction
Temperature

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