Article
E2F-dependent transcription of the raf proto-oncogene during Drosophila development.
Nucleic acids research - 15 Apr 2001
Kwon E J, Oh E J, Kim Y S, Hirose F, Ohno K, Nishida Y, Matsukage A, Yamaguchi M, Yoo M A
Abstract excerpt
D-raf, a Drosophila homolog of the raf proto-oncogene, has diverse functions throughout development and is transcribed in a wide range of tissues, with high levels of expression in the ovary and in association with rapid proliferation. The expression pattern resembles those of S phase genes, which are regulated by E2F transcription factors. In the 5'-flanking region of D-raf, four sequences (E2F sites 1-4)...
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