Article
Certain HLA-DR5 and -DR6 major histocompatibility complex class II alleles are associated with a CD8 lymphocytic host response to human immunodeficiency virus type 1 characterized by low lymphocyte viral strain heterogeneity and slow disease progression.
Proceedings of the National Academy of Sciences of the United States of America - 22 Nov 1994
Itescu S, Rose S, Dwyer E, Winchester R
Abstract excerpt
Either of two structurally related major histocompatibility complex class II alleles, DRB1*1102, which encodes a DR5 specificity, or DRB1*1301, which encodes a DR6 specificity, was found in 67% of individuals responding to human immunodeficiency virus type 1 (HIV-1) infection with a syndrome characterized by persistent circulating and diffusely infiltrative CD8 lymphocytosis (DILS), slow progression to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.