Article
Human leukocyte antigen-DQ alleles and haplotypes and their associations with resistance and susceptibility to HIV-1 infection.
AIDS (London, England) - 23 Apr 2008
Hardie Rae-Anne, Luo Ma, Bruneau Brigitte, Knight Erin, Nagelkerke Nico J D, Kimani Joshua, Wachihi Charles, Ngugi Elizabeth N, Plummer Francis A
Abstract excerpt
OBJECTIVES: To determine the association of DQ antigens with resistance and susceptibility to HIV-1. DESIGN: Despite repeated exposure to HIV-1, a subset of women in the Pumwani Sex Worker cohort established in Nairobi, Kenya in 1985 have remained HIV-1 negative for at least 3 years and are classified as resistant. Differential susceptibility to HIV-1 infection is associated with HIV-1 specific CD4 and CD8 T cell...
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