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Article

Genetic determinants of HIV‐1 infection and progression to AIDS: immune response genes

18 Sept 2009

Abstract excerpt

Genomic studies involving well-defined multicenter cohorts of HIV-1/AIDS covering multiple populations have led to a greater understanding of the role of host determinants in viral acquisition, disease progression, transmission, and response to anti-retroviral therapy. Similarly, recent knowledge on the virus genetic diversity has helped in elucidating mechanisms leading to the evolution of viral escape mutants...

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PMID: 19765261
DOI: 10.1111/j.1399-0039.2009.01337.x

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