Article
Biological basis of the HLA-B8,DR3-associated progression of acquired immune deficiency syndrome.
Pathobiology : journal of immunopathology, molecular and cellular biology - 1 Jan 1998
Candore G, Romano G C, D'Anna C, Di Lorenzo G, Gervasi F, Lio D, Modica M A, Potestio M, Caruso C
Abstract excerpt
The factors influencing the evolution of human immunodeficiency virus (HIV) infection are not fully known, but the host genotype undoubtedly plays a role in determining the outcome of the disease by affecting the immune response to HIV. The role of the host human leukocyte antigen (HLA) genotype in the regulation of susceptibility to HIV infection and expression has been studied extensively in different major...
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