Article
Suppression of tumorigenicity of a human lung carcinoma line by nontumorigenic bronchial epithelial cells in somatic cell hybrids.
Cancer research - 15 Mar 1990
Kaighn M E, Gabrielson E W, Iman D S, Pauls E A, Harris C C
Abstract excerpt
Hybrid cell lines between HuT292-DM, a human lung carcinoma line resistant to 6-thioguanine and ouabain, and either normal human bronchial epithelial cells (NHBE) or an SV40 "immortalized" but nontumorigenic derivative thereof (BEAS-2B), have been isolated by double selection. Hybrids of NHBE and...
Topics
- Animals
- Bronchi
- Cell Division
- Cell Fusion
- Cell Line
- Epithelial Cells
- Genetic Markers
- Humans
- Hybrid Cells
- Karyotyping
- Lung Neoplasms
- Mice
- Mice, Nude
- Mutation
- Tumor Cells, Cultured