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Article

DNA replication arrest and tolerance to DNA methylation damage.

Carcinogenesis - 1 Oct 1994

Zhukovskaya N, Branch P, Aquilina G, Karran P

Abstract excerpt

Inhibition of DNA replication by different DNA damaging agents has been investigated in HeLaMR cells and a methylation damage-tolerant variant HeLa5A1. In synchronous HeLaMR and HeLa5A1 cells exposed to N-ethyl-N-nitrosourea or ionizing radiation in mid-G1 phase, DNA synthesis was inhibited in the following S phase. N-methyl-N-nitrosourea-induced replication inhibition in HeLaMR cells was delayed until the second...

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Source

Identifiers

PMID: 7955052
DOI: 10.1093/carcin/15.10.2189

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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