Apparent alterations in the early stage of excision repair of UV-induced DNA damages in a HeLa mutant cell line that is resistant to genotoxic stresses.

doi:10.1016/0165-7992(93)90004-f

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Article

Apparent alterations in the early stage of excision repair of UV-induced DNA damages in a HeLa mutant cell line that is resistant to genotoxic stresses.

Mutation research - 1 Sept 1993

Chao C C, Huang S L

Abstract excerpt

We have previously reported a cisplatin-resistant HeLa cell line featuring a cross-resistance to genotoxic stresses including ultraviolet (UV) radiation and an enhancement of plasmid reactivation. In this study, excision repair of UV-DNA adducts in this resistant cell line was investigated. Using...

Topics

Cisplatin
DNA Damage
DNA Repair
DNA, Neoplasm
Drug Resistance
HeLa Cells
Humans
Mutation
Ultraviolet Rays

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