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Article

A microplate version of the DNA-synthesis inhibition test for rapid detection of DNA-alteration potentials.

Analytical biochemistry - 1 Jun 1990

Heil J, Reifferscheid G, Pischtschan E, Klös M, Jungblut H D, Zahn R K

Abstract excerpt

A microplate version of the DNA-synthesis inhibition test (DIT) for fast detection of DNA-alteration potentials has been developed. The DIT is based on the concept that DNA damage causes inhibition of DNA synthesis that becomes detectable some time after replicating cells have been in contact with genotoxic agents. In this test procedure human tissue culture cells (HeLa S3), prelabeled with [14C]thymidine, arfe...

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PMID: 2382833
DOI: 10.1016/0003-2697(90)90462-i

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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