Article
Cell cycle regulation in response to DNA damage in mammalian cells: a historical perspective.
Cancer metastasis reviews - 1 Mar 1995
Murnane J P
Abstract excerpt
Cell cycle delay has long been known to occur in mammalian cells after exposure to DNA-damaging agents. It has been hypothesized that the function of this delay is to provide additional time for repair of DNA before the cell enters critical periods of the cell cycle, such as DNA synthesis in S ph...
Topics
- Animals
- Apoptosis
- Ataxia Telangiectasia
- Caffeine
- Cell Cycle
- Cell Cycle Proteins
- DNA Damage
- DNA Repair
- Gene Expression Regulation
- Humans
- Mammals
- Mutation
- Tumor Suppressor Protein p53