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Article

Cell cycle regulation in response to DNA damage in mammalian cells: a historical perspective.

Cancer metastasis reviews - 1 Mar 1995

Murnane J P

Abstract excerpt

Cell cycle delay has long been known to occur in mammalian cells after exposure to DNA-damaging agents. It has been hypothesized that the function of this delay is to provide additional time for repair of DNA before the cell enters critical periods of the cell cycle, such as DNA synthesis in S phase or chromosome condensation in G2 phase. Recent evidence that p53 protein is involved in the delay in G1 in response...

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Identifiers

PMID: 7606817
DOI: 10.1007/BF00690208

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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