The Drosophila tumor suppressor gene dlg is required for normal synaptic bouton structure.

doi:10.1016/0896-6273(94)90249-6

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Article

The Drosophila tumor suppressor gene dlg is required for normal synaptic bouton structure.

Neuron - 1 Oct 1994

Lahey T, Gorczyca M, Jia X X, Budnik V

Abstract excerpt

The Drosophila tumor suppressor gene lethal (1) discs large (dlg) encodes a protein necessary for normal cell growth in epithelial and brain tissue. It shares high sequence identity to the mammalian synaptic proteins PSD-95 and SAP-70, whose functions are unknown. To determine the localization an...

Topics

Animals
Drosophila
Drosophila Proteins
Female
Gene Expression
Genes, Tumor Suppressor
Insect Hormones
Microscopy, Electron
Mutation
Neuromuscular Junction
Presynaptic Terminals
Synaptic Membranes
Tumor Suppressor Proteins

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