Article
The Drosophila tumor suppressor gene, dlg, is involved in structural plasticity at a glutamatergic synapse.
Current biology : CB - 1 Jun 1996
Guan B, Hartmann B, Kho Y H, Gorczyca M, Budnik V
Abstract excerpt
BACKGROUND: Synaptic contacts between neurons and their targets are dynamic entities that can change depending on developmental and functional states of the pre- and postsynaptic cell. However, the molecular factors involved in this plasticity have remained largely unknown. We have demonstrated previously that the Drosophila tumor suppressor gene, discs-large (dlg), is expressed at neuromuscular synapses, and is...
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