Organizing a functional junctional complex requires specific domains of the Drosophila MAGUK Discs large.

Abstract excerpt

Discs large (Dlg) was the first identified member of an increasingly important class of proteins called membrane-associated guanylate kinase homologs (MAGUKs), which are often concentrated at cell junctions and contain distinct peptide domains named PDZ1-3, SH3, HOOK, and GUK. Dlg is localized at and required for the formation of both septate junctions in epithelial cells and synaptic junctions in neurons. In the...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Binding Sites
• Share to Chromosome Mapping
• Share to Drosophila