Article
The Notch ligand E3 ligase, Mind Bomb1, regulates glutamate receptor localization in Drosophila.
Molecular and cellular neurosciences - 1 Jan 2016
Sturgeon Morgan, Davis Dustin, Albers Amanda, Beatty Derek, Austin Rik, Ferguson Matt, Tounsel Brittany, Liebl Faith L W
Abstract excerpt
The postsynaptic density (PSD) is a protein-rich network important for the localization of postsynaptic glutamate receptors (GluRs) and for signaling downstream of these receptors. Although hundreds of PSD proteins have been identified, many are functionally uncharacterized. We conducted a reverse genetic screen for mutations that affected GluR localization using Drosophila genes that encode homologs of mammalian...
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