Article
Sulphated and undersulphated heparan sulphate proteoglycans in a Chinese hamster ovary cell mutant defective in N-sulphotransferase.
The Biochemical journal - 1 Oct 1994
Bame K J, Zhang L, David G, Esko J D
Abstract excerpt
The Chinese hamster ovary cell mutant, pgsE-606, synthesizes undersulphated heparan sulphate glycosaminoglycans because of a deficiency in N-sulphotransferase activity [Bame and Esko (1989) J. Biol. Chem. 264, 8059-8065]. We compared the heparan sulphate proteoglycans synthesized by mutant and wi...
Topics
- Animals
- CHO Cells
- Chromatography, Gel
- Chromatography, Ion Exchange
- Clone Cells
- Cricetinae
- Glucosamine
- Glycosaminoglycans
- Heparan Sulfate Proteoglycans
- Heparitin Sulfate
- Membrane Glycoproteins
- Mutation
- Proteoglycans
- Sulfates
- Sulfotransferases
- Sulfur Radioisotopes
- Syndecans
- Tritium