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Article

Structural determinants of heparan sulphate modulation of GDNF signalling.

Growth factors (Chur, Switzerland) - 1 Jan 2000

Davies J A, Yates E A, Turnbull J E

Abstract excerpt

Glial cell line-derived neurotrophic factor (GDNF) has many functions including regulation of kidney morphogenesis and of neuron growth and survival in the enteric, sensory and central nervous systems. Reports of GDNF being used against Parkinson's disease in human patients have sparked intense clinical interest in GDNF signalling. We recently showed that GDNF signalling requires cell surface heparan sulphate...

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Identifiers

PMID: 14708939
DOI: 10.1080/08977190310001621005

Genes

GDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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