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Article

N-linked oligosaccharides are required to produce and stabilize the active form of chondroitin 4-sulphotransferase-1.

The Biochemical journal - 15 May 2005

Yusa Akiko, Kitajima Ken, Habuchi Osami

Abstract excerpt

C4ST-1 (chondroitin 4-sulphotransferase-1) transfers sulphate to position 4 of N-acetylgalactosamine in chondroitin. We showed previously that purified C4ST-1 from the culture medium of rat chondrosarcoma cells was a glycoprotein containing approx. 35% N-linked oligosaccharides. In the present paper, we investigated the functional role of the N-linked oligosaccharides attached to C4ST-1. We found that (i)...

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Identifiers

PMID: 15628971
DOI: 10.1042/BJ20041573
PMCID: PMC1186699

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Source receipt: pubmed, retrieved 7 Sept 2026.

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