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Article

No linkage between multiple sclerosis and the T cell receptor alpha chain locus.

Journal of the neurological sciences - 1 Jun 1994

Eoli M, Wood N W, Kellar-Wood H F, Holmans P, Clayton D, Compston D A

Abstract excerpt

Susceptibility to multiple sclerosis (MS) is genetically determined but it is thought that more than one gene contributes to development of the disease. We report a study of linkage to one candidate, the T cell receptor alpha chain locus, on chromosome 14, in affected sibling pairs. Markers with high polymorphism information contents were used to assign haplotypes identical by descent and state. Forty nine pairs...

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Identifiers

PMID: 7931419
DOI: 10.1016/0022-510x(94)90007-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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No linkage between multiple sclerosis and the T cell receptor alpha chain locus.PMID 7931419Read ↗

T cell receptor alpha chain polymorphisms in multiple sclerosis.Semantic proximity Read ↗

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Association of protein kinase C alpha (PRKCA) gene with multiple sclerosis in a UK population.Semantic proximity Read ↗

Revisiting the T-cell receptor alpha/delta locus and possible associations with multiple sclerosis.Semantic proximity Read ↗

T-cell receptor alpha chain germline gene polymorphisms in multiple sclerosis.Semantic proximity Read ↗

No evidence to support CTLA-4 as a susceptibility gene in MS families: the Canadian Collaborative Study.Semantic proximity Read ↗

Linkage between T cell receptor genes and susceptibility to multiple sclerosis: a complex issue.Semantic proximity Read ↗

Linkage and association analysis of susceptibility regions on chromosomes 5 and 6 in 106 Scandinavian sibling pair families with multiple sclerosis.Semantic proximity Read ↗

Susceptibility to multiple sclerosis and the immunoglobulin heavy chain variable region.Semantic proximity Read ↗

Parental non-inherited HLA resistance alleles do not confer protection against multiple sclerosis.Semantic proximity Read ↗

Discordance of T-cell receptor beta-chain genes in familial multiple sclerosis.Semantic proximity Read ↗

HLA and T-cell receptor polymorphisms in Belgian multiple sclerosis patients: no evidence for disease association with the T-cell receptor.Semantic proximity Read ↗

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