T cell receptor alpha chain polymorphisms in multiple sclerosis.

doi:10.1016/0165-5728(92)90211-3

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Article

T cell receptor alpha chain polymorphisms in multiple sclerosis.

Journal of neuroimmunology - 1 Sept 1992

Hashimoto L L, Mak T W, Ebers G C

Abstract excerpt

Numerous studies have implicated the major histocompatibility complex (MHC) class II alleles, DR2 and DQw1, as multiple sclerosis (MS) susceptibility loci, however, the involvement of other loci is implied by twin studies and the relative lack of haplotype sharing for MHC. To evaluate the role th...

Topics

Alleles
Gene Frequency
Genotype
Haplotypes
Humans
Multiple Sclerosis
Polymorphism, Genetic
Receptors, Antigen, T-Cell, alpha-beta

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