T-cell receptor alpha, beta, gamma, and delta chain gene microsatellites show no association with multiple sclerosis.

doi:10.1212/wnl.47.4.1049

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Article

T-cell receptor alpha, beta, gamma, and delta chain gene microsatellites show no association with multiple sclerosis.

Neurology - 1 Oct 1996

Droogan A G, Kirk C W, Hawkins S A, McMillan S A, Nevin N C, Graham C A

Abstract excerpt

Genetic predisposition to multiple sclerosis (MS) is determined, in part, by certain HLA genotypes, but the contribution of T-cell receptor (TCR) germline polymorphisms to MS susceptibility is less clear. Reports of disease associations with restriction fragment length polymorphisms of TCR alpha...

Topics

Alleles
Humans
Microsatellite Repeats
Multiple Sclerosis
Receptors, Antigen, T-Cell

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