Article
T-cell receptor alpha, beta, gamma, and delta chain gene microsatellites show no association with multiple sclerosis.
Neurology - 1 Oct 1996
Droogan A G, Kirk C W, Hawkins S A, McMillan S A, Nevin N C, Graham C A
Abstract excerpt
Genetic predisposition to multiple sclerosis (MS) is determined, in part, by certain HLA genotypes, but the contribution of T-cell receptor (TCR) germline polymorphisms to MS susceptibility is less clear. Reports of disease associations with restriction fragment length polymorphisms of TCR alpha and beta chain genes have been difficult to confirm, and little data is available on the influence of the TCR gamma...
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