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Article

Association of protein kinase C alpha (PRKCA) gene with multiple sclerosis in a UK population.

Brain : a journal of neurology - 1 Aug 2004

Barton A, Woolmore J A, Ward D, Eyre S, Hinks A, Ollier W E R, Strange R C, Fryer A A, John S, Hawkins C P, Worthington J

Abstract excerpt

Twin, family and adoption studies suggest that susceptibility to multiple sclerosis is substantially mediated by genetic factors. Linkage to human chromosome 17q, homologous to a locus linked to experimental animal models of multiple sclerosis, has been widely replicated and the region likely to harbour a multiple sclerosis susceptibility gene has recently been refined to a 2.5 Mb region of 17q22-24. The...

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Identifiers

PMID: 15155525
DOI: 10.1093/brain/awh193

Genes

PRKCA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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