T-cell receptor alpha chain germline gene polymorphisms in multiple sclerosis.

doi:10.1212/wnl.42.1.80

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Article

T-cell receptor alpha chain germline gene polymorphisms in multiple sclerosis.

Neurology - 1 Jan 1992

Hillert J, Leng C, Olerup O

Abstract excerpt

It has been proposed that genetic predisposition to multiple sclerosis (MS) and other diseases with autoimmune features is conferred by T-cell receptor (TcR) genes in addition to HLA class II genes. Although a family study has suggested linkage of susceptibility to MS to TcR genes, reports of dis...

Topics

Alleles
Chronic Disease
Genotype
HLA-DR2 Antigen
Haplotypes
Humans
Multiple Sclerosis
Polymorphism, Genetic
Polymorphism, Restriction Fragment Length
Receptors, Antigen, T-Cell, alpha-beta
Recurrence

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