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Article

Linkage between T cell receptor genes and susceptibility to multiple sclerosis: a complex issue.

Regional immunology - 1 Jan 2000

Robinson M A, Kindt T J

Abstract excerpt

Susceptibility to Multiple Sclerosis (MS) and to other autoimmune diseases has been linked to genes encoded within the HLA complex. More recent evidence indicates linkage between MS and genes encoded within or closely linked to the T cell receptor (TCR) beta chain gene complex. However, not all available data are concordant. Discrepancies are most likely rooted in the complex nature of TCR and MHC genes and...

Topics

Genetic Linkage
Genetic Variation
Humans
Immunogenetics
Multigene Family
Multiple Sclerosis
Polymorphism, Genetic
Receptors, Antigen, T-Cell
T-Lymphocytes

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1290747

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1290747-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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