Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of systemic interferon-alpha (IFN-alpha) on the antigenic phenotype of melanoma metastases. EORTC melanoma group cooperative study No. 18852.

Melanoma research - 1 Jun 1993

von Stamm U, Bröcker E B, von Depka Prondzinski M, Ruiter D J, Rümke P, Broding C, Carrel S, Lejeune F J

Abstract excerpt

In order to investigate the effects of in vivo treatment with interferon-alpha (IFN-alpha) on melanoma antigens, a clinical EORTC trial (No. 18852) was accompanied by an immunohistological study. Twenty patients with melanoma metastases of skin and soft tissues, eventually also of the lung, who were treated with systemic IFN-alpha, were evaluated for a comparison of metastases before (40) and during (42)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Antibodies, Monoclonal

Share to Antigens, Neoplasm

Share to HLA-DR Antigens

Share to Immunohistochemistry

Share to Melanoma

Share to Neoplasm Proteins

Source

Identifiers

PMID: 8104570
DOI: 10.1097/00008390-199306000-00005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of systemic interferon-alpha (IFN-alpha) on the antigenic phenotype of melanoma metastases. EORTC melanoma group cooperative study No. 18852.PMID 8104570Read ↗

Low-dose IFN-gamma induces tumor MHC expression in metastatic malignant melanoma.Semantic proximity Read ↗

Modulation of the antigenic phenotype of early-passage human melanoma cells derived from multiple autologous metastases by recombinant human leukocyte, fibroblast and immune interferon.Semantic proximity Read ↗

Immunomodulatory effects of high-dose and low-dose interferon alpha2b in patients with high-risk resected melanoma: the E2690 laboratory corollary of intergroup adjuvant trial E1690.Semantic proximity Read ↗

Unbalanced expression of HLA-A and -B antigens: a specific feature of cutaneous melanoma and other non-hemopoietic malignancies reverted by IFN-gamma.Semantic proximity Read ↗

Immunohistological analysis of anti-melanoma host responses.Semantic proximity Read ↗

Locus-Specific Analysis of Human Leukocyte Antigen Class I Expression in Melanoma Cell LinesSemantic proximity Read ↗

Regulation of the antigenic phenotype of human melanoma cells by recombinant interferons.Semantic proximity Read ↗

Immunohistochemical phenotyping of malignant melanoma. A procedure whose time has come in pathology practice.Semantic proximity Read ↗

HLA class I alleles and responsiveness of melanoma to immunotherapy with interferon-alpha (IFN-alpha) and interleukin-2 (IL-2).Semantic proximity Read ↗

Phenotypic heterogeneity of HLA products on human melanoma cells.Semantic proximity Read ↗

Activation markers on T cells infiltrating melanoma metastases after therapy with dinitrophenyl-conjugated vaccine.Semantic proximity Read ↗

Alteration of melanoma cell phenotype following in vitro culturing and exposure to cytostatic agents.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.