Article
Frequency and prognostic evaluation of 3p21-22 allelic losses in non-small-cell lung cancer.
International journal of cancer - 20 Dec 1995
Thiberville L, Bourguignon J, Metayer J, Bost F, Diarra-Mehrpour M, Bignon J, Lam S, Martin J P, Nouvet G
Abstract excerpt
Previous loss of heterozygosity (LOH) studies of chromosome 3p loci have displayed a 60% deletion frequency in non-small-cell lung cancers (NSCLC), as opposed to small-cell lung cancers, in which the 3p deletion is consistently found. However, the high stromal-cell admixture found in NSCLC and th...
Topics
- Alleles
- Base Sequence
- Carcinoma, Non-Small-Cell Lung
- Chromosomes, Human, Pair 3
- Gene Deletion
- Genetic Markers
- Heterozygote
- Humans
- Lung Neoplasms
- Microsatellite Repeats
- Molecular Sequence Data
