A single frizzled protein has a dual function in tissue polarity.

doi:10.1242/dev.120.7.1883

Back to search

Article

A single frizzled protein has a dual function in tissue polarity.

Development (Cambridge, England) - 1 Jul 1994

Krasnow R E, Adler P N

Abstract excerpt

The Drosophila frizzled (fz) gene is required for the development of normal tissue polarity in the epidermis. Genetic epistasis experiments argue that fz is at the top of a regulatory hierarchy that controls the subcellular site for prehair initiation within the cells of the pupal wing (Wong and...

Topics

Animals
Animals, Genetically Modified
Blotting, Western
Drosophila melanogaster
Epidermis
Gene Expression
Genes, Insect
Immunohistochemistry
Microscopy, Electron, Scanning
Morphogenesis
Phenotype

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.