Article
A single frizzled protein has a dual function in tissue polarity.
Development (Cambridge, England) - 1 Jul 1994
Krasnow R E, Adler P N
Abstract excerpt
The Drosophila frizzled (fz) gene is required for the development of normal tissue polarity in the epidermis. Genetic epistasis experiments argue that fz is at the top of a regulatory hierarchy that controls the subcellular site for prehair initiation within the cells of the pupal wing (Wong and Adler, 1993; J. Cell Biol. 123, 209-221). Genetic mosaic experiments indicate that fz has both cell autonomous and cell...
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