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Article

The Drosophila planar polarity gene multiple wing hairs directly regulates the actin cytoskeleton.

Development (Cambridge, England) - 15 Jul 2015

Lu Qiuheng, Schafer Dorothy A, Adler Paul N

Abstract excerpt

The evolutionarily conserved frizzled/starry night (fz/stan) pathway regulates planar cell polarity (PCP) in vertebrates and invertebrates. This pathway has been extensively studied in the Drosophila wing, where it is manifested by an array of distally pointing cuticular hairs. Using in vivo imaging we found that, early in hair growth, cells have multiple actin bundles and hairs that subsequently fuse into a...

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Identifiers

PMID: 26153232
DOI: 10.1242/dev.122119
PMCID: PMC4510862

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The Drosophila planar polarity gene multiple wing hairs directly regulates the actin cytoskeleton.PMID 26153232Read ↗

The multiple-wing-hairs gene encodes a novel GBD-FH3 domain-containing protein that functions both prior to and after wing hair initiation.Semantic proximity Read ↗

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The Drosophila planar polarity proteins inturned and multiple wing hairs interact physically and function together.Semantic proximity Read ↗

The frizzled/stan pathway and planar cell polarity in the Drosophila wing.Semantic proximity Read ↗

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