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Article

Molecular structure of frizzled, a Drosophila tissue polarity gene.

Genetics - 1 Oct 1990

Adler P N, Vinson C, Park W J, Conover S, Klein L

Abstract excerpt

The function of the frizzled (fz) locus is required to coordinate the cytoskeletons of pupal epidermal cells so that a parallel array of cuticular hairs and bristles is produced. We report here the molecular cloning and characterization of the fz locus. The locus is very large. Mutations that inactivate the gene are spread over 100 kb of genomic DNA. The major mRNA product of the gene is a 4-kb RNA that is...

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Identifiers

PMID: 2174014
DOI: 10.1093/genetics/126.2.401
PMCID: PMC1204194

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Molecular structure of frizzled, a Drosophila tissue polarity gene.PMID 2174014Read ↗

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The cold-sensitive period for frizzled in the development of wing hair polarity ends prior to the start of hair morphogenesis.Semantic proximity Read ↗

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