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Article

Molecular analysis of EMS-induced frizzled mutations in Drosophila melanogaster.

Genetics - 1 Jan 1996

Jones K H, Liu J, Adler P N

Abstract excerpt

The frizzled (fz) gene of Drosophila is essential for the development of normal tissue polarity in the adult cuticle of Drosophila. In fz mutants the parallel array of hairs and bristles that decorate the cuticle is disrupted. Previous studies have shown the fz encodes a membrane protein with seven putative transmembrane domains, and that it has a complex role in the development of tissue polarity, as there exist...

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Identifiers

PMID: 8770598
DOI: 10.1093/genetics/142.1.205
PMCID: PMC1206949

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