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Article

Signaling specificity by Frizzled receptors in Drosophila.

Science (New York, N.Y.) - 9 Jun 2000

Boutros M, Mihaly J, Bouwmeester T, Mlodzik M

Abstract excerpt

Wnt-Frizzled (Fz) signaling pathways play recurring important roles during the development and homeostasis of vertebrates and invertebrates. Fz receptors can signal through beta-catenin-dependent and -independent pathways. In Drosophila, Fz and Fz2 are redundant receptors for Wg. In addition, Fz conveys signals through a distinct pathway to organize planar polarization of epithelial structures. We demonstrate...

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Identifiers

PMID: 10846164
DOI: 10.1126/science.288.5472.1825

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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