Article
The cold-sensitive period for frizzled in the development of wing hair polarity ends prior to the start of hair morphogenesis.
Mechanisms of development - 1 May 1994
Adler P N, Charlton J, Jones K H, Liu J
Abstract excerpt
The function of the frizzled (fz) gene is essential for the development of the normal pattern of hairs on the Drosophila wing. In the absence of fz function hairs develop, but they display an abnormal polarity. Mutations in fz result in an altered subcellular location for the assembly of the F-actin filled prehair that becomes the adult cuticular hair. This observation led to the suggestion that fz and other...
Topics
- Actins
- Alleles
- Amino Acid Sequence
- Animals
- Arginine
- Blotting, Western
- Drosophila
- Drosophila Proteins
- Frizzled Receptors
- Gene Expression Regulation, Developmental
- Genes, Insect