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Article

Cell fate determination. When is a determinant a determinant?

Current biology : CB - 1 May 1994

Cohen S, Hyman A A

Abstract excerpt

The Numb protein, which is asymmetrically distributed during certain cell divisions in the nervous system of Drosophila, may have a role in determining the developmental fates of the daughter cells.

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Identifiers

PMID: 7922356
DOI: 10.1016/s0960-9822(00)00091-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cell fate determination. When is a determinant a determinant?PMID 7922356Read ↗

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Notch regulates numb: integration of conditional and autonomous cell fate specification.Semantic proximity Read ↗

Localization-dependent and -independent roles of numb contribute to cell-fate specification in Drosophila.Semantic proximity Read ↗

Binary sibling neuronal cell fate decisions in the Drosophila embryonic central nervous system are nonstochastic and require inscuteable-mediated asymmetry of ganglion mother cells.Semantic proximity Read ↗

The Multitasker Protein: A Look at the Multiple Capabilities of NUMBSemantic proximity Read ↗

Neural cell fate in rca1 and cycA mutants: the roles of intrinsic and extrinsic factors in asymmetric division in the Drosophila central nervous system.Semantic proximity Read ↗

Sanpodo and Notch act in opposition to Numb to distinguish sibling neuron fates in the Drosophila CNS.Semantic proximity Read ↗

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At the nexus between pattern formation and cell-type specification: the generation of individual neuroblast fates in the Drosophila embryonic central nervous system.Semantic proximity Read ↗

Bazooka is required for localization of determinants and controlling proliferation in the sensory organ precursor cell lineage in Drosophila.Semantic proximity Read ↗

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