Article
Mutations in sigma factor that affect the temperature dependence of transcription from a promoter, but not from a mismatch bubble in double-stranded DNA.
Biochemistry - 27 Sept 1994
Aiyar S E, Juang Y L, Helmann J D, deHaseth P L
Abstract excerpt
Specificity of promoter utilization in bacterial RNA polymerases is imparted by a class of proteins referred to as sigma factors. Conserved region 2.3 of these proteins is thought to play a role in the strand separation process that occurs during the formation of an initiation-competent RNA polym...
Topics
- Amino Acid Sequence
- Bacillus subtilis
- Base Sequence
- Cold Temperature
- DNA, Bacterial
- DNA, Single-Stranded
- DNA-Directed RNA Polymerases
- Escherichia coli
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation