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Article

Structural basis for -10 promoter element melting by environmentally induced sigma factors.

Nature structural & molecular biology - 1 Mar 2014

Campagne Sébastien, Marsh May E, Capitani Guido, Vorholt Julia A, Allain Frédéric H-T

Abstract excerpt

Bacterial transcription is controlled by sigma factors, the RNA polymerase subunits that act as initiation factors. Although a single housekeeping sigma factor enables transcription from thousands of promoters, environmentally induced sigma factors redirect gene expression toward small regulons to carry out focused responses. Using structural and functional analyses, we determined the molecular basis of -10...

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PMID: 24531660
DOI: 10.1038/nsmb.2777

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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