Article
Crystal structure of a sigma 70 subunit fragment from E. coli RNA polymerase.
Cell - 4 Oct 1996
Malhotra A, Severinova E, Darst S A
Abstract excerpt
The 2.6 A crystal structure of a fragment of the sigma 70 promoter specificity subunit of E. coli RNA polymerase is described. Residues involved in core RNA polymerase binding lie on one face of the structure. On the opposite face, aligned along one helix, are exposed residues that interact with the -10 consensus promoter element (the Pribnow box), including four aromatic residues involved in promoter melting....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.