Article
[Detection of Ki-ras oncogene mutations in normal mucosa, adenoma and adenocarcinoma of the colon].
Zhonghua bing li xue za zhi = Chinese journal of pathology - 1 Dec 1993
Wang Z Y
Abstract excerpt
Paraffin embedded tissues, including 41 surgically resected colonic specimens in which separable normal mucosa, adenoma and adenocarcinoma were available, and 10 endoscopically excised colonic adenomas were studied for Ki-ras mutations by RFLP, SSCP and S1 nuclease protection methods. Mutations o...
Topics
- Adenocarcinoma
- Adenoma
- Base Sequence
- Colonic Neoplasms
- DNA, Neoplasm
- Female
- Genes, ras
- Humans
- Male
- Middle Aged
- Molecular Sequence Data
- Mutation
- Polymorphism, Restriction Fragment Length
