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Article

c-Ki-ras gene mutations in dysplasia and carcinomas complicating ulcerative colitis.

British journal of cancer - 1 Jul 1991

Bell S M, Kelly S A, Hoyle J A, Lewis F A, Taylor G R, Thompson H, Dixon M F, Quirke P

Abstract excerpt

One hundred and nine samples comprising carcinomas, adenomas, dysplastic, inflamed and normal mucosa from patients with sporadic colon cancer and ulcerative colitis (UC) were analysed for c-Ki-ras mutations. DNA was extracted from archival paraffin-embedded material, amplified using the polymerase chain reaction (PCR) and the PCR products analysed using restriction enzyme digestion. Forty-two per cent (14/33) of...

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Identifiers

PMID: 1854618
DOI: 10.1038/bjc.1991.264
PMCID: PMC1977292

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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