c-Ki-ras gene mutations in dysplasia and carcinomas complicating ulcerative colitis.

doi:10.1038/bjc.1991.264

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Article

c-Ki-ras gene mutations in dysplasia and carcinomas complicating ulcerative colitis.

British journal of cancer - 1 Jul 1991

Bell S M, Kelly S A, Hoyle J A, Lewis F A, Taylor G R, Thompson H, Dixon M F, Quirke P

Abstract excerpt

One hundred and nine samples comprising carcinomas, adenomas, dysplastic, inflamed and normal mucosa from patients with sporadic colon cancer and ulcerative colitis (UC) were analysed for c-Ki-ras mutations. DNA was extracted from archival paraffin-embedded material, amplified using the polymeras...

Topics

Codon
Colitis, Ulcerative
Colon
Colonic Neoplasms
DNA, Neoplasm
Genes, ras
Humans
Mutation
Neoplasm Staging
Polymerase Chain Reaction
Rectal Neoplasms
Restriction Mapping

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