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Article

c-Ki-ras mutations in chronic ulcerative colitis and sporadic colon carcinoma.

Gastroenterology - 1 Aug 1990

Burmer G C, Levine D S, Kulander B G, Haggitt R C, Rubin C E, Rabinovitch P S

Abstract excerpt

Mutations in the first exon of the c-Ki-ras protooncogene were analyzed in carcinomas and dysplasias from patients with sporadic colon cancer and chronic ulcerative colitis by a combination of histological enrichment, cell sorting, polymerase catalyzed chain reaction, and direct sequencing. In contrast to sporadic colon carcinomas, where 52% (11 of 21) contained mutations in codon 12, only 1 of 28 samples of...

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Identifiers

PMID: 2194896
DOI: 10.1016/0016-5085(90)91024-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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