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Article

[Mutation analysis of K-ras protooncogene in colorectal adenocarcinomas and polyps in Russian patients].

Genetika - 1 May 2010

Amosenko F A, Korchagina E L, Matveeva T I, Vaganov Iu E, Vlasov S B, Poltavets N V, Veselov V V, Gar'kavtseva R F, Poliakov A V

Abstract excerpt

To estimate diagnostic value of K-ras mutations during cancer risk group formation, they were studied in the samples of sporadic carcinomas (n = 33) and malignant (n = 13) polyps of large intestine obtained during surgery or polypectomy. Using PCR analysis, restriction analysis, SSCP analysis and automated sequencing, eight various point mutations were revealed. Six of them were located in codon 12 and two, in...

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PMID: 20583607

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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