Article
[Mutation analysis of K-ras protooncogene in colorectal adenocarcinomas and polyps in Russian patients].
Genetika - 1 May 2010
Amosenko F A, Korchagina E L, Matveeva T I, Vaganov Iu E, Vlasov S B, Poltavets N V, Veselov V V, Gar'kavtseva R F, Poliakov A V
Abstract excerpt
To estimate diagnostic value of K-ras mutations during cancer risk group formation, they were studied in the samples of sporadic carcinomas (n = 33) and malignant (n = 13) polyps of large intestine obtained during surgery or polypectomy. Using PCR analysis, restriction analysis, SSCP analysis and...
Topics
- Adenocarcinoma
- Adult
- Age Factors
- Aged
- Codon
- Colonic Polyps
- Colorectal Neoplasms
- DNA Mutational Analysis
- DNA, Neoplasm
- Female
- Genes, ras
- Humans
