Article
Rapid HLA-DQB1 genotyping for four alleles in the assessment of risk for IDDM in the Finnish population. The Childhood Diabetes in Finland (DiMe) Study Group.
Diabetes care - 1 Aug 1996
Ilonen J, Reijonen H, Herva E, Sjöroos M, Iitiä A, Lövgren T, Veijola R, Knip M, Akerblom H K
Abstract excerpt
OBJECTIVE: To study the effectiveness of MHC genotyping in the assessment of risk for IDDM based on the identification of alleles that are significantly associated with risk for IDDM (DQB1 *0302 and *0201) and protection from it (DQB1 *0602/*0603 and *0301). RESEARCH DESIGN AND METHODS: A long se...
Topics
- Alleles
- DNA
- Diabetes Mellitus, Type 1
- Disease Progression
- Finland
- Genotype
- HLA-DQ Antigens
- HLA-DQ beta-Chains
- Humans
- Nuclear Family
- Reference Values
- Risk Assessment